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A Sequence Based Validation of Gene Expression Microarray Data

Gerhard G. Thallinger — 2012-01-19

Current Research in Bioinformatics, Published online: 19 January 2012; doi:10.3844/ajbsp.2012.1.9

Problem statement: Quantitative Reverse Transcription PCR (RT-qPCR) is often used to validate microarray data. Previous studies show different levels of correlation, without further investigation of i...

Bioinformatics-Assisted Microbiological Research: Tasks, Developments and Upcoming Challenges

Dhananjaya P. Singh — 2012-01-23

Current Research in Bioinformatics, Published online: 23 January 2012; doi:10.3844/ajbsp.2012.10.19

Problem statement: Bioinformatics in the present day microbiological research is an inevitable subject area that encompasses biological resources and high end computational skills to unravel the coded...

Use of Enterobacterial Repetitive Intergenic Consensus PCR in Detecting Target(s) of Hapalindole-T, From a Cyanobacterium, in Escherichia Coli: In Silico Validation

Manoj K. Tripathi — 2012-03-03

Current Research in Bioinformatics, Published online: 3 March 2012; doi:10.3844/ajbsp.2012.30.40

Problem statement: Identification of newer biomolecule as well as targets are a rising concern because of increasing drug resistance in bacteria. We have isolated a broad spectrum antibiotic biomolecu...

Using Threads to Overcome Synchronization Delays in Parallel Multiple Progressive Alignment Algorithms

Evandro A. Marucci — 2012-03-08

Current Research in Bioinformatics, Published online: 8 March 2012; doi:10.3844/ajbsp.2012.50.63

Problem statement: The parallelization of multiple progressive alignment algorithms is a difficult task. All known methods have strong bottlenecks resulting from synchronization delays. This is even m...

Ten Bioinformatics Tools for Single Nucleotide Polymorphisms Detection

Mahin Ghorbani — 2015-04-10

Current Research in Bioinformatics, Published online: 10 April 2015; doi:10.3844/ajbsp.2014.45.48

Single Nucleotide Polymorphisms (SNPs) as unique genetic variations are widely used as biomarkers for drug designing and development for individualized therapy. SNP genotyping techniques such as SBE w...